Thursday, July 2, 2009

Pathology

http://library.med.utah.edu/WebPath/RENAHTML/RENAL156.html

Kimmelstiel-Wilson lesion


Diabetic nephropathy:
This is nodular glomerulosclerosis (the Kimmelstiel-Wilson lesion) of diabetes mellitus. Nodules of pink hyaline material form in regions of glomerular capillary loops in the glomerulus. This is due to a marked increase in mesangial matrix from damage as a result of non-enzymatic glycosylation of proteins.