Wednesday, October 14, 2009

Wire loop lesion in SLE

http://books.google.com/books?id=VAjCbLmODJgC&pg=PA56&lpg=PA56&dq=wire+loop+lupus&source=bl&ots=H2Zw9zmLDN&sig=tV37NXPWRkBBIKtBXgncjCcA5ZU&hl=en&ei=qmjWSrSVN4qOswOU2dzGAg&sa=X&oi=book_result&ct=result&resnum=6&ved=0CBoQ6AEwBQ#v=onepage&q=wire%20loop%20lupus&f=false

Thursday, July 2, 2009

Pathology

http://library.med.utah.edu/WebPath/RENAHTML/RENAL156.html

Kimmelstiel-Wilson lesion


Diabetic nephropathy:
This is nodular glomerulosclerosis (the Kimmelstiel-Wilson lesion) of diabetes mellitus. Nodules of pink hyaline material form in regions of glomerular capillary loops in the glomerulus. This is due to a marked increase in mesangial matrix from damage as a result of non-enzymatic glycosylation of proteins.